Among 14,807 eligible babies born to GBS-positive mothers between 2006 and 2018, 311 had received antibiotics. The researchers compared these babies with a matched subset (n = 933) of the untreated group. Controlling for ethnicity, socioeconomic status, mode of delivery, birth weight, maternal asthma, and antibiotic use during pregnancy, postnatal antibiotic exposure was associated with ~30% higher risk for asthma in regression (relative risk (RR), 1.3; 95% CI, 1.04-1.6; P = .018) and propensity (RR, 1.31; 95% CI, 1.01-1.69; P = .039) statistical models. In addition, the antibiotic-treated babies were more than twice as likely to develop allergic rhinitis.
“The link between antibiotic use and asthma is convincing, and this poster adds to the supportive evidence,” said James Gern, MD, professor of pediatrics and medicine at the School of Medicine and Public Health, University of Wisconsin-Madison.
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